Platelet activation in subjects carrying factor V Leiden or factor II A20210 mutations
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چکیده
منابع مشابه
Genetic Thrombophilia Lower birth-weight in neonates of mothers carrying factor V G1691A and factor II A20210 mutations
ELVIRA GRANDONE,* MAURIZIO MARGAGLIONE,* DONATELLA COLAIZZO,* GIUSEPPE PAVONE,° DARIO PALADINI,° PASQUALE MARTINELLI,° GIOVANNI DI MINNO* *Unità di Aterosclerosi e Trombosi and Obstetrics and Gynecology Department, IRCCS “Casa Sollievo della Sofferenza”, S. Giovanni Rotondo (FG); °Obstetrics and Gynecology Department, Università “Federico II”, Naples, Italy Correspondence: Elvira Grandone, MD, ...
متن کاملthe association of coagulation factor v (leiden) and factor ii (prothrombin) mutations with stroke
conclusions the prevalence of both fv and fii variants are population based. iran is an ethnically diverse country. therefore, for a comprehensive analysis of a potential association of fv and/or fii mutations with stroke among iranian population, epidemiological studies could be conducted among different ethnic groups. patients and methods the study population consisted of 153 patients of diff...
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A polymorphism in coagulation factor V, factor V Leiden (FVL), is the major known genetic risk factor for thrombosis in humans. Approximately 10% of mutation carriers experience clinically significant thrombosis in their lifetime. In a small subset of patients, thrombosis is associated with coinheritance of other prothrombotic gene mutations. However, the potential contribution of additional ge...
متن کاملFrequency of Factor II G20210A and Factor V Leiden Mutations in Algerian Patients with Venous Thromboembolism
Several inherited polymorphisms are associated with the risk of venous thrombosis, including mutation at codon 506 of the factor V gene and mutation at position 20210 of the prothrombin gene. The aim of this study was to determine the frequency of factor II G20210A and factor V Leiden mutations in Algerian patients with venous thromboembolism disease. In this study, genotyping for factor V Leid...
متن کاملThe Association of Coagulation Factor V (Leiden) and Factor II (Prothrombin) Mutations With Stroke
BACKGROUND Epidemiological studies indicate that over the past forty years, the stroke incidence rates has increased. Factors V and II mutations are established genetic-variant risk factors for venous thrombosis; however, their contribution to stroke is a controversial issue. OBJECTIVES This study aimed to investigate the potential association of FV and FII mutations with stroke in an Iranian...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2006
ISSN: 1538-7933,1538-7836
DOI: 10.1111/j.1538-7836.2006.02191.x